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2004-5-10 · National Center for High Throughput Screening (HTS) of Novel Bioactive Compounds "The main goal of the Center is to establish a focused, multidisciplinary drug discovery unit, which will coordinate the collection of biological material from diverse and unique sources, isolation of novel natural products and screening these products for

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  • National Center For High Throughput   Screening (HTS)

    National Center For High Throughput Screening (HTS)

    2004-5-10 · National Center for High Throughput Screening (HTS) of Novel Bioactive Compounds "The main goal of the Center is to establish a focused, multidisciplinary drug discovery unit, which will coordinate the collection of biological material from diverse and unique sources, isolation of novel natural products and screening these products for

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  • Industrial Scale Screening   Accelerates Discovery Of

    Industrial Scale Screening Accelerates Discovery Of

    Industrial-Scale Screening Accelerates Discovery of Novel Drug Combination Therapies. In a single software environment, the AstraZeneca Oncology iMed Unit has a complete processing workflow for compound combination experiments from small-scale studies in drug projects to high-throughput combination screening in a centralised team. It

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  • A   Novel, Automated Nutrition Screening System As A ..

    A Novel, Automated Nutrition Screening System As A ..

    Purpose. Paper-based nutrition screening tools can be challenging to implement in the ambulatory oncology setting. The aim of this study was to determine the validity of the Malnutrition Screening Tool (MST) and a novel, automated nutrition screening system compared to a ‘gold standard’ full nutrition assessment using the Patient-Generated Subjective Global Assessment (PG-SGA).

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  • Turku Screening Unit   Awarded Funding To Expand

    Turku Screening Unit Awarded Funding To Expand

    2019-9-16 · The Screening Unit, in affiliation with Biocentre Finland Drug Discovery and Chemical Biology of Biocity Turku, has been awarded funding to greatly expand its robotic screening capabilities. The unit will acquire upgrades to automate the efficient assembly and measurement of assays for library and cherry-picked screening campaigns.

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  • An In Vitro Screening Assay To   Discover Novel Inhibitors ..

    An In Vitro Screening Assay To Discover Novel Inhibitors ..

    An in vitro screening assay to discover novel inhibitors of 4-coumarate: Biological Research Unit, Research & Development Division, Nihon Nohyaku Co. Ltd, 345 Oyamada, Kawachi-Nagano, Osaka 586-0094, Japan The process of this assay can be developed into a high-throughput screening system of PGI targeting 4CL in the phenylpropanoid

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  • A Novel Multi Parametric   High Content Screening

    A Novel Multi Parametric High Content Screening

    A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery we report the development of a high content screening assay in ciPTEC-OAT1, a proximal tubular cell line that expresses several relevant renal transporters, using five fluorescent dyes to quantify cell health

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  • Screening And Evolution Of   A Novel Protist Xylose ..

    Screening And Evolution Of A Novel Protist Xylose ..

    Screening and evolution of a novel protist xylose isomerase from the termite Reticulitermes speratus for efficient xylose fermentation in Saccharomyces cerevisiae. Satoshi Katahira 1, Nobuhiko Muramoto 1, Shigeharu Moriya 2, Risa Nagura 1, One unit (U) of enzyme activity

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  • Screening And   Characterization Of Fungal Cellulases Isolated ..

    Screening And Characterization Of Fungal Cellulases Isolated ..

    2011-5-9 · Screening and characterization of fungal cellulases isolated from the native environmental source (Lederberg, 1992). In industry, these enzymes have found novel

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  • Guidelines For Cervical Screening   In New Zealand

    Guidelines For Cervical Screening In New Zealand

    Guidelines for Cervical Screening in New Zealand 9 Overview of Cervical Screening in New Zealand I n New Zealand, approximately 160 women are diagnosed with cervical cancer every year and 60 die from this largely preventable disease, despite the availability of an organised screening programme.

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  • Modified Asphaltene Capillary Deposition   Unit: A

    Modified Asphaltene Capillary Deposition Unit: A

    2015-9-24 · Asphaltene deposition in capillaries is a tool that has been used in an attempt to better understand asphaltene deposition in the field. However, data reproducibility and inhibitor ranking present some challenges with this technique. An improved asphaltene capillary deposition unit and a novel experimental protocol were developed to address these problems and are presented here.

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  • Virtual Screening:   Development Of A Novel Structure

    Virtual Screening: Development Of A Novel Structure

    2017-10-17 · discover similar structures from the screening database. In this thesis a novel method for virtual screening was developed, which employs structural and chemical information of the binding site of the protein. In addition, several different methods were evaluated for their efficiency in virtual screening

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  • Label Free Detection Microarray For   Novel Peptide

    Label Free Detection Microarray For Novel Peptide

    Therefore, the bi-unit microarray chip was designed for the imprinting of both the two SPRi chips. Compare to the single unit chip, the screening throughput was multiplied. 800 beads in 800 wells could be detected simultaneously. The detection area of the SPRi chip was limited (1.4 cm×1.4 cm) which was suitable for only one unit duplication.

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  • A Review Of Novel Biological Tools   Used In Screening For ..

    A Review Of Novel Biological Tools Used In Screening For ..

    A review of novel biological tools used in screening for the early detection of lung cancer R Ghosal, 1,2P Kloer,1 K E Lewis 1 Respiratory Unit, Prince Philip Hospital, Hywel Dda NHS Trust, Llanelli, Wales, UK; 2 School of Medicine, University of

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  • An In Vitro Screening Assay To   Discover Novel Inhibitors ..

    An In Vitro Screening Assay To Discover Novel Inhibitors ..

    An in vitro screening assay to discover novel inhibitors of 4-coumarate: Biological Research Unit, Research & Development Division, Nihon Nohyaku Co. Ltd, 345 Oyamada, Kawachi-Nagano, Osaka 586-0094, Japan The process of this assay can be developed into a high-throughput screening system of PGI targeting 4CL in the phenylpropanoid

    Get Details
  • Optical Screening Of   Novel Bacteria Specific Probes On

    Optical Screening Of Novel Bacteria Specific Probes On

    2017-11-30 · Our model used ex vivo human lung tissue and a clinically approved confocal laser endomicroscopy (CLE) platform to screen novel bacteria-specific imaging compounds, closely mimicking imaging conditions expected to be encountered with patients. Therefore, screening compounds by this technique provides confidence of potential clinical tractability.

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  • A Novel Screening Method   To Identify Late Stage

    A Novel Screening Method To Identify Late Stage

    2018-3-15 · A Novel Screening Method to Identify Late-Stage Dementia Patients for Palliative Care Research and Practice Natalie C. Ernecoff, MPH, Kathryn L. Wessell, BA, Stacey Gabriel, MPH, Timothy S. Carey, MD, MPH, and Laura C. Hanson, MD, MPH

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  • Today

    Today's Out Of Reach Protein Targets Made Accessible.

    2019-1-8 · SEAL™ consists of novel technologies for antigen design , potent immunogen preparation, efficient animal immunization, and large-scale antibody screening to produce

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  • Home   | Drug Discovery Unit

    Home | Drug Discovery Unit

    2019-9-15 · The University of Dundee Drug Discovery Unit is a fully operational, fully integrated drug discovery group working across multiple disease areas. We collaborate with partners to translate world-class biology research into novel drug targets and candidate drugs to address unmet medical need across our two areas of activity,

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  • 2001: A Space Odyssey   (novel)   Wikipedia

    2001: A Space Odyssey (novel) Wikipedia

    2019-9-9 · 2001: A Space Odyssey is a 1968 science fiction novel by British writer Arthur C. Clarke.It was developed concurrently with Stanley Kubrick's film version and published after the release of the film. Clarke and Kubrick worked on the book together, but eventually only Clarke ended up

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  • Optical Screening Of   Novel Bacteria Specific Probes On

    Optical Screening Of Novel Bacteria Specific Probes On

    2017-11-30 · Our model used ex vivo human lung tissue and a clinically approved confocal laser endomicroscopy (CLE) platform to screen novel bacteria-specific imaging compounds, closely mimicking imaging conditions expected to be encountered with patients. Therefore, screening compounds by this technique provides confidence of potential clinical tractability.

    Get Details
  • A Review Of Novel Biological Tools   Used In Screening For ..

    A Review Of Novel Biological Tools Used In Screening For ..

    A review of novel biological tools used in screening for the early detection of lung cancer R Ghosal, 1,2P Kloer,1 K E Lewis 1 Respiratory Unit, Prince Philip Hospital, Hywel Dda NHS Trust, Llanelli, Wales, UK; 2 School of Medicine, University of

    Get Details
  • E Screening Revolution: A   Novel Approach To

    E Screening Revolution: A Novel Approach To

    Objectives: Delirium is common in the intensive care unit (ICU), often affecting older patients. A bedside electronic tool has the potential to revolutionise delirium screening. Our group describe a novel approach to the design and development of delirium screening questions for the express purpose of use within an electronic device.

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  • A Novel Screening Method   To Identify Late Stage

    A Novel Screening Method To Identify Late Stage

    A Novel Screening Method to Identify Late-Stage Dementia Patients for Palliative Care Research and Practice. Certain groups of seriously ill patients are clustered within a specific nursing unit, clinic or physician practice, but many serious illness populations are

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  • Research | Bioactivity   Screening | University Of Helsinki

    Research | Bioactivity Screening | University Of Helsinki

    We are also hosting the Bioactivity Screening Unit, which provides researchers access to screening instrumentation as well as consultation in matters such as compound libraries, screening assay development and quality control relevant for screening campaigns. This unit belongs to the Drug Discovery and Chemical Biology network, and is a HiLIFE

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  • A Novel Inhibitor Of   Tumorspheres Reveals The Activation ..

    A Novel Inhibitor Of Tumorspheres Reveals The Activation ..

    EDITOR’S CHOICE A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition Amit Subedi1, Makoto Muroi1, Yushi Futamura1, Tatsuro Kawamura2, Harumi Aono1, Mayuko Nishi3, Akihide Ryo3, Nobumoto Watanabe2,4 and Hiroyuki Osada1,2 1 Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science,

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  • Infrared And Raman Screening Of   Seized Novel

    Infrared And Raman Screening Of Seized Novel

    TY - JOUR. T1 - Infrared and Raman screening of seized novel psychoactive substances. T2 - a large scale study of 200 samples. AU - Jones, Louise E.

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  • Comparison Of A Novel,   Simple Nutrition Screening Tool For ..

    Comparison Of A Novel, Simple Nutrition Screening Tool For ..

    2014-12-3 · Comparison of a novel, simple nutrition screening tool for adult oncology inpatients and the Malnutrition Screening Tool (MST) ificity of the screening tools and to identify the proportion of ment and Statistics Unit the day before recruitment to the study.

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  • A Qualified Success: Discovery Of A New Series Of

    A Qualified Success: Discovery Of A New Series Of

    2019-8-9 · The bromodomain of ATAD2 has proved to be one of the least-tractable proteins within this target class. Here, we describe the discovery of a new class of inhibitors by high-throughput screening and show how the difficulties encountered in establishing a screening triage capable of finding progressible hits were overcome by data-driven optimization.

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